Identification and validation of key autophagy-related genes in lupus nephritis by bioinformatics and machine learning.

Journal: PloS one

PMID: 39869603

Abstract

INTRODUCTION: Lupus nephritis (LN) is one of the most frequent and serious organic manifestations of systemic lupus erythematosus (SLE). Autophagy, a new form of programmed cell death, has been implicated in a variety of renal diseases, but the relationship between autophagy and LN remains unelucidated.

Authors

Su Zhang
Weitao Hu

Department of Rheumatology, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, P.R. China.
Yelin Tang

General Hospital of Ningxia Medical University, Yinchuan, P.R. China.
Xiaoqing Chen

College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, China.

Keywords

Animals Autophagy Computational Biology Female Gene Expression Profiling Gene Regulatory Networks Humans Kidney Lupus Nephritis Machine Learning Mice Protein Interaction Maps Transcriptome

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View on PubMed Access via DOI PubMed (39869603)

Identification and validation of key autophagy-related genes in lupus nephritis by bioinformatics and machine learning.

Abstract

Authors

Keywords

External Resources

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