Prediction Trough Concentrations of Valproic Acid Among Chinese Adult Patients with Epilepsy Using Machine Learning Techniques.

Journal: Pharmaceutical research
PMID:

Abstract

OBJECTIVE: This study aimed to establish an optimal model based on machine learning (ML) to predict Valproic acid (VPA) trough concentrations in Chinese adult epilepsy patients.

Authors

  • Nannan Yao
    Department of Pharmacy, Jinshan Hospital Affiliated to Fudan University, Shanghai, China.
  • Qiongyue Zhao
    Department of Pharmacy, Jinshan Hospital Affiliated to Fudan University, Shanghai, China.
  • Ying Cao
  • Dongshi Gu
    Department of Pharmacy, Jinshan Hospital Affiliated to Fudan University, Shanghai, China. 1336768470@qq.com.
  • Ning Zhang
    Institute of Nuclear Agricultural Sciences, Zhejiang University, Hangzhou, 310058, China.