Artificial intelligence-based analysis of retinal fluid volume dynamics in neovascular age-related macular degeneration and association with vision and atrophy.

Journal: Eye (London, England)
PMID: 39406933

Abstract

BACKGROUND/OBJECTIVES: To characterise morphological changes in neovascular age-related macular degeneration (nAMD) during anti-angiogenic therapy and explore relationships with best-corrected visual acuity (BCVA) and development of macular atrophy (MA).

Authors

  • Siqing Yu
    F. Hoffmann-La Roche Ltd, Basel, Switzerland.
  • Ian Lloyd Jones
    F. Hoffmann-La Roche Ltd, Basel, Switzerland.
  • Andreas Maunz
    Pharma Research and Early Development (pRED), Roche Innovation Center Basel, Basel, Switzerland.
  • Isabel Bachmeier
    F. Hoffmann-La Roche Ltd, Basel, Switzerland.
  • Thomas Albrecht
    Institute of Pathology, Heidelberg University, Heidelberg, Germany.
  • Andreas Ebneter
    F. Hoffmann-La Roche Ltd, Basel, Switzerland.
  • Martin Gliem
    F. Hoffmann-La Roche Ltd, Basel, Switzerland.
  • Giovanni Staurenghi
    Department of Biomedical and Clinical Sciences Luigi Sacco, Luigi Sacco Hospital, University of Milan, Italy.
  • SriniVas R Sadda
    Doheny Image Analysis Laboratory, Doheny Eye Institute, Los Angeles, CA, USA.
  • Usha Chakravarty
    Queens University of Belfast, Belfast, Northern Ireland.
  • Sascha Fauser
    F. Hoffmann-La Roche Ltd, Basel, Switzerland. sascha.fauser@roche.com.

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