DCTP-Net: Dual-Branch CLIP-Enhance Textual Prompt-Aware Network for Acute Ischemic Stroke Lesion Segmentation From CT Image.

Journal: IEEE journal of biomedical and health informatics
Published Date:

Abstract

Detecting early ischemic lesions (EIL) in computed tomography (CT) images is crucial for reducing diagnostic time and minimizing neuron loss due to oxygen deprivation. This paper introduces DCTP-Net, a dual-branch network for segmenting acute ischemic stroke lesions in CT images, consisting of a segmentation branch and a prompt-aware branch. The segmentation branch uses an encoder-decoder network as the backbone to identify lesions, where the encoder fuses CT image features with prompt features from the prompt-aware branch. To enhance semantic feature extraction and reduce the impact of cerebral structural details, we introduce a cross-collaboration dynamic connection (CCDC) module to link the encoder and decoder. The prompt-aware branch includes a learnable prompt (LP) block to incorporate cerebral prior knowledge, and the prompt-aware encoder (PAE) combines the LP block with multi-level features from the segmentation branch for more precise representation. Additionally, we propose a CLIP-enhance textual prompt (CETP) module that utilizes the CLIP text encoder to generate specialized convolutional parameters for the segmentation head. These parameters are tailored to the unique characteristics of each input image, improving segmentation performance. Qualitative and quantitative studies reveal that DCTP-Net outperforms the current state-of-the-art, IS-Net, with Dice score increases of 3.9% on AISD and 3.8% on ISLES2018, demonstrating its superiority in EIL segmentation.

Authors

  • Jiahao Liu
    School of Artificial Intelligence, Hebei University of Technology, Tianjin, 300130, China.
  • Hongqing Zhu
    School of Information Science and Engineering, East China University of Science and Technology, Shanghai 200237, China.
  • Ziying Wang
    MOE Key Laboratory of Standardization of Chinese Medicines, SATCM Key Laboratory of New Resources and Quality Evaluation of Chinese Medicines, Shanghai Key Laboratory of Compound Chinese Medicine, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
  • Ning Chen
    Department of General Surgery, Peking University Third Hospital, Beijing, P. R. China.
  • Tong Hou
  • Bingcang Huang
  • Weiping Lu
    Laboratory Department, Daping Hosipital, Army Medical University, Chongqing, 400042, China.
  • Ying Wang
    Key Laboratory of Macromolecular Science of Shaanxi Province, School of Chemistry & Chemical Engineering, Shaanxi Normal University, Xi'an, Shaanxi 710062, China.
  • Suyi Yang