Identification of miR-20a as a Diagnostic and Prognostic Biomarker in Colorectal Cancer: MicroRNA Sequencing and Machine Learning Analysis.

Journal: MicroRNA (Shariqah, United Arab Emirates)
PMID:

Abstract

INTRODUCTION: The differential expression of miRNAs, a key regulator in many cell signaling pathways, has been studied in various malignancies and may have an important role in cancer progression, including colorectal cancer (CRC).

Authors

  • Hamid Jamialahmadi
    Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
  • Alireza Asadnia
    Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
  • Ghazaleh Khalili-Tanha
    Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran; Medical Genetics Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
  • Reza Mohit
    Department of Anesthesia, Bushehr University of Medical Sciences, Bushehr, Iran.
  • Hanieh Azari
    Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
  • Majid Khazaei
    Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
  • Mina Maftooh
    Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
  • Mohammadreza Nassiri
    Recombinant Proteins Research Group, The Research Institute of Biotechnology, Ferdowsi University of Mashhad, Mashhad, Iran.
  • Seyed Mahdi Hassanian
    Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
  • Majid Ghayour-Mobarhan
    International UNESCO Center for Health Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.
  • Gordon A Ferns
    Brighton & Sussex Medical School, Division of Medical Education, Falmer, Brighton, Sussex BN1 9PH, UK.
  • Elham Nazari
    Proteomics Research Center, System Biology Institute, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Elham.Nazari@sbmu.ac.ir.
  • Amir Avan
    Molecular Medicine Group, Department of Modern Sciences and Technologies, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.