Post-Mortem imaging biobanks: Building data for reproducibility, standardization, and AI integration.

Journal: European journal of radiology
PMID: 40031379

Abstract

In recent years, post-mortem imaging has advanced with techniques such as Post-Mortem Computed Tomography (PMCT) and Post-Mortem Magnetic Resonance imaging (PMMR). PMCT is particularly useful for assessing skeletal injuries, vascular lesions, and estimating post-mortem intervals. These analyses are based on radiomics principles, a growing field that requires specialized expertise, which is still limited. To support this field, post-mortem imaging biobanks are proposed as valuable tools, especially when enhanced with Artificial Intelligence (AI). However, complexities in this field require caution and adherence to guidelines, especially regarding consent for image storage, participant information, international cooperation, and nonprofit operations.

Authors

  • Fabio De-Giorgio
    Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy; Department of Healthcare Surveillance and Bioethics, Section of Legal Medicine, Università Cattolica del Sacro Cuore, Rome, Italy. Electronic address: fabio.degiorgio@unicatt.it.
  • Beatrice Benedetti
    Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy; Department of Healthcare Surveillance and Bioethics, Section of Legal Medicine, Università Cattolica del Sacro Cuore, Rome, Italy.
  • Matteo Mancino
    Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy; Department of Diagnostic Imaging, Oncological Radiotherapy and Hematology, Università Cattolica del Sacro Cuore, Rome, Italy.
  • Evis Sala
    Department of Radiology and Cancer Research UK Cambridge Centre, University of Cambridge, Box 218, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0QQ, England.
  • Vincenzo L Pascali
    Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy; Department of Healthcare Surveillance and Bioethics, Section of Legal Medicine, Università Cattolica del Sacro Cuore, Rome, Italy.

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