Deciphering the role of cuproptosis in the development of intimal hyperplasia in rat carotid arteries using single cell analysis and machine learning techniques.

Journal: Scientific reports
PMID:

Abstract

UNLABELLED: This study aims to explore the regulatory role of cuproptosis in carotid intimal hyperplasia (IH), providing new insights into its pathophysiological mechanisms and potential diagnostic and therapeutic strategies.

Authors

  • Miao He
    Department of Ultrasonic Medicine, Fetal Medical Center, First Affiliated Hospital of Sun Yat-sen University, Zhongshan Er Road 58, Guangzhou, 510080, Guangdong, China.
  • Hui Chen
    Xiangyang Central HospitalAffiliated Hospital of Hubei University of Arts and Science Xiangyang 441000 China.
  • Zhengli Liu
    Department of Interventional Radiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, Jiangsu, People's Republic of China.
  • Boxiang Zhao
    Department of Interventional Radiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, Jiangsu, People's Republic of China.
  • Xu He
    Interconnected & Integrated Bioelectronics Lab (IBL), Department of Electrical and Computer Engineering, University of California, Los Angeles, CA, USA.
  • Qiujin Mao
    Department of General Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, Jiangsu, People's Republic of China. njsdyyyjrk@163.com.
  • Jianping Gu
    Department of Interventional Radiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, Jiangsu, People's Republic of China. cjr.gujianping@163.com.
  • Jie Kong