Fanconi anemia (FA) is an inherited bone marrow failure syndrome with cancer predisposition. Most FA patients develop aplastic anemia during childhood and have an extremely high cumulative risk to develop cancer during their lifespan. Myeloid maligna...
Artificial intelligence (AI) has become a transformative tool in cell biology, driving discoveries through the analysis of complex biological data. This review explores the diverse applications of AI, including its impact on microscopy, imaging, drug...
Prostate cancer exhibits a strong familial association, and its heritability indicates a significant contribution from germline variants. While genome-wide association studies (GWAS) have identified common germline variants associated with prostate c...
BACKGROUND: Periodontitis (PD) is a chronic, multifactorial inflammatory disorder characterized by the progressive destruction of periodontal tissues. Increasing evidence indicates that the dysregulation of hypoxia-related genes (HRGs) plays a pivota...
Cell sorting, essential for diagnostics and early intervention, has evolved from conventional methods to sophisticated microfluidic approaches. These miniaturized systems leverage precise hydrodynamic control, facilitating major advances in tumor cel...
Biochemical and biophysical research communications
Dec 17, 2025
The dry fruits of Amomum villosum (Av) are a traditional Chinese medicine used for gastrointestinal disease. Aromatic oil has been reported to have anti-tumor properties. However, its therapeutic potential and molecular mechanisms remain unclear. Int...
UNLABELLED: Single-cell RNA sequencing (scRNA-seq) technology enables researchers to explore heterogeneity of diverse cell types within complex tissues at the single-cell resolution. Cell annotation, as a crucial step in scRNA-seq data analysis, prov...
Early detection of lung cancer is crucial for improving patient outcomes. However, accurately diagnosing invasive pulmonary nodules and predicting tumor invasiveness remain major clinical challenges. Given the established role of immune dysfunction i...
High-spatial-resolution mass spectrometry imaging (MSI) visualizes molecular distributions in tissues and cells. However, achieving higher spatial resolution typically necessitates smaller pixel dimensions and an increased number of pixels, leading t...
BACKGROUND: Non-small cell lung cancer (NSCLC) is one of the most prevalent malignancies and currently shows a poor clinical prognosis. Type II pneumocyte, as one of the main sources of cancer cells in NSCLC, is important to explore the molecular fun...
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