Prediction of Chemotherapy Response in Locally Advanced Breast Cancer Patients at Pre-Treatment Using CT Textural Features and Machine Learning: Comparison of Feature Selection Methods.

Journal: Tomography (Ann Arbor, Mich.)
PMID: 40137573

Abstract

RATIONALE: Neoadjuvant chemotherapy (NAC) is a key element of treatment for locally advanced breast cancer (LABC). Predicting the response of NAC for patients with LABC before initiating treatment would be valuable to customize therapies and ensure the delivery of effective care.

Authors

  • Amir Moslemi
    Department of Physics, Toronto Metropolitan University, Ontario, Canada; School of Software Design & Data Science, Seneca Polytechnic, Toronto, ON, M4N 3M5, Canada; Physical Sciences, Sunnybrook Health Sciences Centre, Toronto, ON, M4N 3M5, Canada. Electronic address: amsu1392@gmail.com.
  • Laurentius Oscar Osapoetra
    Physical Sciences, Sunnybrook Research Institute, Toronto, ON M4N 3M5, Canada.
  • Archya Dasgupta
    Physical Sciences, Sunnybrook Research Institute, Toronto, ON M4N 3M5, Canada.
  • Schontal Halstead
    Physical Sciences, Sunnybrook Research Institute, Toronto, ON M4N 3M5, Canada.
  • David Alberico
    Physical Sciences, Sunnybrook Research Institute, Toronto, ON M4N 3M5, Canada.
  • Maureen Trudeau
    Department of Medical Oncology, Department of Medicine, Sunnybrook Health Sciences Centre, Toronto, ON M4N 3M5, Canada.
  • Sonal Gandhi
    Division of Medical Oncology, 71545Sunnybrook Health Sciences Centre, Toronto, Canada.
  • Andrea Eisen
    Department of Medical Oncology, Department of Medicine, Sunnybrook Health Sciences Centre, Toronto, ON M4N 3M5, Canada.
  • Frances Wright
    Department of Surgical Oncology, Department of Surgery, Sunnybrook Health Sciences Centre, Toronto, ON M4N 3M5, Canada.
  • Nicole Look-Hong
    Department of Surgical Oncology, Department of Surgery, Sunnybrook Health Sciences Centre, Toronto, ON M4N 3M5, Canada.
  • Belinda Curpen
    Division of Breast Imaging, 71545Sunnybrook Health Sciences Centre, Toronto, Canada.
  • Michael Kolios
    Department of Physics, Toronto Metropolitan University, Toronto, ON M5B 2K3, Canada.
  • Gregory J Czarnota
    Physical Sciences, Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, ON, Canada.

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