Identifying Lipid Metabolism-Related Therapeutic Targets and Diagnostic Markers for Lung Adenocarcinoma by Mendelian Randomization and Machine Learning Analysis.

Journal: Thoracic cancer
PMID: 40107973

Abstract

BACKGROUND: Lipid metabolic disorders are emerging as a recognized influencing factors of lung adenocarcinoma (LUAD). This study aims to investigate the influence of lipid metabolism-related genes (LMRGs) on the diagnosis and treatment of LUAD and to identify significant biomarkers.

Authors

  • Su Wei
    Department of Endoscopy, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, China.
  • Zhou Guangyao
    Key Laboratory of Cancer Prevention and Therapy, Tianjin, China.
  • Tian Xiangdong
    Department of Endoscopy, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, China.
  • Guo Feng
    Department of Endoscopy, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, China.
  • Zhang Lianmin
    Key Laboratory of Cancer Prevention and Therapy, Tianjin, China.
  • Zhang Zhenfa
    Key Laboratory of Cancer Prevention and Therapy, Tianjin, China.

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