Eye Movement Characteristics for Predicting a Transition to Psychosis: Longitudinal Changes and Implications.

Journal: Schizophrenia bulletin
Published Date:

Abstract

BACKGROUND AND HYPOTHESIS: Substantive inquiry into the predictive power of eye movement (EM) features for clinical high-risk (CHR) conversion and their longitudinal trajectories is currently sparse. This study aimed to investigate the efficiency of machine learning predictive models relying on EM indices and examine the longitudinal alterations of these indices across the temporal continuum.

Authors

  • Dan Zhang
    School of Pharmacy, Southwest Medical University, Luzhou 646000, China.
  • Lihua Xu
    Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
  • Xu Liu
    School of Electrical and Electronic Engineering, Nanyang Technological University, Singapore 639798, Singapore. liuxu16@bjut.edu.cn.
  • Huiru Cui
    Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
  • Yanyan Wei
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, Singapore 637371, Singapore.
  • Wensi Zheng
    Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
  • Yawen Hong
    Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
  • Zhenying Qian
    Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
  • Yegang Hu
    Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
  • Yingying Tang
    Shanghai Mental Health Center, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.
  • Chunbo Li
    Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University.
  • Zhi Liu
  • Tao Chen
    School of Automation, Northwestern Polytechnical University, Xi'an, 710072, Shaanxi, China.
  • Haichun Liu
    Laboratory of Molecular Design and Drug Discovery, School of Science, China; Pharmaceutical University, 639 Longmian Avenue, Nanjing, 211198 Jiangsu, China.
  • Tianhong Zhang
    Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Engineering Research Center of Intelligent Psychological Evaluation and Intervention, Shanghai Jiaotong University School of Medicine, Shanghai, PR China.
  • Jijun Wang
    Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.