Prediction of Reactivation After Antivascular Endothelial Growth Factor Monotherapy for Retinopathy of Prematurity: Multimodal Machine Learning Model Study.

Journal: Journal of medical Internet research
PMID: 40267476

Abstract

BACKGROUND: Retinopathy of prematurity (ROP) is the leading preventable cause of childhood blindness. A timely intravitreal injection of antivascular endothelial growth factor (anti-VEGF) is required to prevent retinal detachment with consequent vision impairment and loss. However, anti-VEGF has been reported to be associated with ROP reactivation. Therefore, an accurate prediction of reactivation after treatment is urgently needed.

Authors

  • Rong Wu
    Department of Ultrasound, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Yu Zhang
    College of Marine Electrical Engineering, Dalian Maritime University, Dalian, China.
  • Peijie Huang
    School of Information Engineering, Guangdong University of Technology, Guangzhou, China.
  • Yiying Xie
    School of Information Engineering, Guangdong University of Technology, Guangzhou, China.
  • Jianxun Wang
    Department of Aerospace and Mechanical Engineering, University of Notre Dame, Notre Dame, IN 46556.
  • Shuangyong Wang
    Department of Ophthalmology, Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
  • Qiuxia Lin
    Department of Ophthalmology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
  • Yichen Bai
    Department of Ophthalmology, Zhujiang Hospital, Southern Medical University, No.253 Gongyedadao Middle Road City, Guangzhou, Guangdong, 510282, China.
  • Songfu Feng
    Department of Ophthalmology, Zhujiang Hospital of Southern Medical University, Guangzhou, China.
  • Nian Cai
    School of Information Engineering, Guangdong University of Technology, Guangzhou, China.
  • Xiaohe Lu
    Department of Ophthalmology, Zhujiang Hospital of Southern Medical University, Guangzhou, China.

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