Understanding Transient Left Ventricular Ejection Fraction Reduction During Atrial Fibrillation With Artificial Intelligence.

Journal: Journal of the American Heart Association
Published Date: May 13, 2025

Abstract

BACKGROUND: Atrial fibrillation (AF) can cause a reduction in left ventricular ejection fraction (LVEF) that resolves rapidly upon restoration of sinus rhythm. We used artificial intelligence to understand (1) how often transient LVEF reduction during AF is from mismeasurement due to AF's beat-to-beat variability and (2) whether true transient AF-LVEF reduction has prognostic significance.

Authors

  • Neal Yuan
    Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Gloria J Hong
    Cedars-Sinai Smidt Heart Institute Los Angeles CA USA.
  • Amey Vrudhula
    Icahn School of Medicine at Mount Sinai, New York (A.V.).
  • Alan C Kwan
    Department of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA.
  • Grant Duffy
    Department of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, 127 S San Vicente Blvd A3600, Los Angeles, CA 90048, United States.
  • Patrick Botting
    Department of Cardiology, Cedars-Sinai Medical Center, Los Angeles, California, United States of America.
  • Sanket S Dhruva
    Robert Wood Johnson Foundation Clinical Scholars Program, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, United States of America.
  • Robert J Siegel
    Cedars-Sinai Smidt Heart Institute Los Angeles CA USA.
  • David Ouyang
    Division of Artificial Intelligence, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA.

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