Dedicated AI Expert System vs Generative AI With Large Language Model for Clinical Diagnoses.

Journal: JAMA network open
Published Date: May 1, 2025

Abstract

IMPORTANCE: Large language models (LLMs) have not yet been compared with traditional diagnostic decision support systems (DDSSs) on unpublished clinical cases.

Authors

  • Mitchell J Feldman
    Laboratory of Computer Science, Massachusetts General Hospital, Boston.
  • Edward P Hoffer
    Laboratory of Computer Science, Massachusetts General Hospital, Boston.
  • Jared J Conley
    Laboratory of Computer Science, Massachusetts General Hospital, Boston.
  • Jaime Chang
    Laboratory of Computer Science, Massachusetts General Hospital, Boston.
  • Jeanhee A Chung
    Laboratory of Computer Science, Massachusetts General Hospital, Boston.
  • Michael C Jernigan
    Laboratory of Computer Science, Massachusetts General Hospital, Boston.
  • William T Lester
    Laboratory of Computer Science, Massachusetts General Hospital, Boston.
  • Zachary H Strasser
    Laboratory of Computer Science, Massachusetts General Hospital, Boston, MA, 02144, USA.
  • Henry C Chueh
    Laboratory of Computer Science, Massachusetts General Hospital, 50 Staniford Street, Suite 750, Boston, MA, 02114, USA.

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