Smartphone-integrated Nanozyme approaches for rapid and on-site detection: Empowering smart food safety.

Journal: Food chemistry
Published Date:

Abstract

Smartphone-integrated nanozyme technologies (S-INTs) have emerged as a promising solution for rapid, on-site food safety analysis, addressing the detection of foodborne pathogens, contaminants, and hazards. While the applications of nanozymes in food safety are well-reviewed, their integration with smartphones for real-time biosensing remains underexplored. This review highlights advancements in S-INTs, emphasizing predominant merits such as portability, real-time data processing, and user-friendly interfaces. Recent progress includes detecting pathogens, food additives, nutrients, and hazardous residues like pesticides and veterinary drugs. Furthermore, we explore the potential of combining S-INTs with artificial intelligence (AI), machine learning (ML), deep learning (DL), and 3D printing to enhance detection sensitivity and broaden their applications. Critical challenges such as improving sensitivity, enabling multiplexing, and validating field applications are also discussed. Notably, these advancements hold immense potential to empower smart food safety systems, enabling real-time and on-site detection to ensure food quality and safeguard public health.

Authors

  • Flomo Peter Gbonyea
    College of Biological Engineering, Qingdao University of Science and Technology, Qingdao 266042, China; Faculty of Life Science and Food Engineering, Huaiyin Institute of Technology, Huaian 223003, China.
  • Jiahang Wu
    Faculty of Life Science and Food Engineering, Huaiyin Institute of Technology, Huaian 223003, China.
  • Mengru Li
    Department of Hospital Infection Management Section, Gaochun People's Hospital, Gaochun Hospital Affiliated to Jiangsu University, Nanjing, 211300, China.
  • Mengdi Liang
    State Key Laboratory of Respiratory Disease, Sino-French Hoffmann Institute, School of Basic Medical Science, Guangzhou Medical University, Guangzhou, China.
  • Mingdao Zhang
    Faculty of Life Science and Food Engineering, Huaiyin Institute of Technology, Huaian 223003, China.
  • Xiaoyan Zhu
    Anhui Technical College of Industry and Economy, Hefei, China.
  • Xiangqian Li
    Faculty of Life Science and Food Engineering, Huaiyin Institute of Technology, Huaian 223003, China.
  • Shuai He
    Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, 1 Dongjiaominxiang, Dongcheng District, Beijing, 100730, People's Republic of China.
  • Pei Liu
    School of Life Sciences, Nanjing University, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing 210000, China.