Tumor-infiltrating immune cell signature score reveals prognostic biomarkers and therapeutic targets for colorectal cancer.

Journal: Frontiers in immunology
Published Date: Jan 1, 2025

Abstract

BACKGROUND: Colorectal cancer (CRC) is one of the leading contributors to cancer-related deaths worldwide, with more than 900,000 new diagnoses and related deaths each year. This study aims to explore the prognostic value of tumor-infiltrating immune cell (TIIC)-related genes in CRC, in order to discover new biomarkers and therapeutic targets.

Authors

  • Xiaofei Zuo
    Department of Gastrointestinal Surgery, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
  • Wujun Long
    Department of Gastrointestinal Surgery, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
  • Kai Lin
    Department of Clinical Laboratory, Air Force General Hospital, PLA Beijing 100142, China.
  • Guiqing Jia
    v Department of Gastrointestinal Surgery, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.

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