Using Digital Phenotyping to Discriminate Unipolar Depression and Bipolar Disorder: Systematic Review.

Journal: Journal of medical Internet research
Published Date: May 23, 2025

Abstract

BACKGROUND: Differentiating bipolar disorder (BD) from unipolar depression (UD) is essential, as these conditions differ greatly in their progression and treatment approaches. Digital phenotyping, which involves using data from smartphones or other digital devices to assess mental health, has emerged as a promising tool for distinguishing between these two disorders.

Authors

  • Rongrong Zhong
    Clinical Research Center & Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Xiaohui Wu
    Clinical Research Center & Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China.
  • Jun Chen
    Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA 90095, USA.
  • Yiru Fang
    Clinical Research Center & Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China; CAS Center for Excellence in Brain Science and Intelligence Technology, Shanghai 200031, China; Shanghai Key Laboratory of Psychotic disorders, Shanghai 201108, China. Electronic address: yirufang@aliyun.com.

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