AIMS: The present review explores the existing evidence on pharmacogenomic tests for prediction of lithium response in the treatment of bipolar disorder. We focused our research article on reports describing findings from genome-wide association stud...
BACKGROUND: The genetic determinants of peripartum depression (PPD) are not fully understood. Using a multi-polygenic score approach, we characterized the relationship between genome-wide information and the history of PPD in patients with mood disor...
In a letter critiquing our manuscript, Takefuji highlights general pitfalls in machine learning, without directly engaging with our study. The comments provide generic advice rather than a specific critique of our methods or findings. Despite raising...
International journal of molecular sciences
39684694
Mental health disorders are devastating illnesses, often misdiagnosed due to overlapping clinical symptoms. Among these conditions, bipolar disorder, schizophrenia, and schizoaffective disorder are particularly difficult to distinguish, as they share...
INTRODUCTION: The diagnostic boundaries between schizophrenia and bipolar disorder are controversial due to the ambiguity of psychiatric nosology. From this perspective, it is noteworthy that formal thought disorder has historically been considered p...
INTRODUCTION: Bipolar disorder (BD) and major depressive disorder (MDD) have overlapping clinical presentations which may make it difficult for clinicians to distinguish them potentially resulting in misdiagnosis. This study combined structural MRI a...
BACKGROUND: Bipolar is a severe mental health condition affecting at least 2% of the global population, with clinical observations suggesting that individuals experiencing elevated mood states, such as mania or hypomania, may have an increased propen...
BACKGROUND: Monitoring symptoms of bipolar disorder (BD) is a challenge faced by mental health services. Speech patterns are crucial in assessing the current experiences, emotions, and thought patterns of people with BD. Natural language processing (...
Schizophrenia (SZ) and bipolar disorder (BD) pose diagnostic challenges due to overlapping clinical symptoms and genetic factors, often resulting in misdiagnosis and suboptimal treatment outcomes. This study aimed to identify EEG-based biomarkers tha...
IMPORTANCE: The diagnosis of schizophrenia and bipolar disorder is often delayed several years despite illness typically emerging in late adolescence or early adulthood, which impedes initiation of targeted treatment.