Urinary biomarkers of kidney transplant rejection.

Journal: Current opinion in organ transplantation
Published Date:

Abstract

PURPOSE OF REVIEW: Despite the introduction of many new immunosuppressive medications, allograft rejection remains a significant complication in transplantation. The use of "liquid biopsy" to evaluate allograft function and detect early rejection has recently become a prominent focus of investigation as it holds promise in providing noninvasive and immediate insights into the cellular and molecular makeup of the graft.

Authors

  • Tamara Merhej
    Renal Division, Transplantation Research Center, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
  • Rania El Fekih
  • Jamil R Azzi