AIMC Topic: Liquid Biopsy
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Human multiethnic radiogenomics reveals low-abundancy microRNA signature in plasma-derived extracellular vesicles for early diagnosis and molecular subtyping of pancreatic cancer.
eLife
Aug 8, 2025
Pancreatic cancer (PC) is a highly aggressive malignancy in humans, where early diagnosis significantly improves patient outcomes. However, effective methods for accurate and early detection remain limited. In this multiethnic study involving human s...
Socioeconomic impact of artificial intelligence-driven point-of-care testing devices for liquid biopsy in the OncoCheck system.
Cancer metastasis reviews
Aug 6, 2025
Cancer disparities in low- and middle-income countries (LMICs) persist because of socioeconomic inequalities and limited access to screening infrastructure, which requires equitable diagnostic solutions. As researchers, we need to develop interventio...
Validation of an AI-enabled exome/transcriptome liquid biopsy platform for early detection, MRD, disease monitoring, and therapy selection for solid tumors.
Scientific reports
Jul 1, 2025
Effective clinical management of patients with cancer requires highly accurate diagnosis, precise therapy selection, and highly sensitive monitoring of disease burden. Caris Assure is a multifunctional blood-based assay that couples whole exome and w...
Innovative technologies and their clinical prospects for early lung cancer screening.
Clinical and experimental medicine
Jun 18, 2025
BACKGROUND: Lung cancer remains the leading cause of cancer-related mortality worldwide, due to lacking effective early-stage screening approaches. Imaging, such as low-dose CT, poses radiation risk, and biopsies can induce some complications. Additi...
Liquid Biopsy: The Challenges of a Revolutionary Approach in Oncology.
International journal of molecular sciences
May 23, 2025
Liquid biopsy has gained attention in oncology as a non-invasive diagnostic tool, offering valuable insights into tumor biology through the analysis of circulating nucleic acid (cfDNA and cfRNA), circulating tumor cells (CTCs), extracellular vesicles...
Artificial intelligence-driven integration of multi-omics and radiomics: A new hope for precision cancer diagnosis and prognosis.
Biochimica et biophysica acta. Molecular basis of disease
Apr 9, 2025
Despite advances in cancer diagnosis and treatment, the disease remains a major health challenge. Integrating multi-omics, radiomics, and artificial intelligence has improved detection, prognosis, and treatment monitoring. Molecular multi-omics provi...
Urinary biomarkers of kidney transplant rejection.
Current opinion in organ transplantation
Apr 2, 2025
PURPOSE OF REVIEW: Despite the introduction of many new immunosuppressive medications, allograft rejection remains a significant complication in transplantation. The use of "liquid biopsy" to evaluate allograft function and detect early rejection has...
Nano biosensor unlocks tumor derived immune signals for the early detection of ovarian cancer.
Biosensors & bioelectronics
Mar 10, 2025
Ovarian cancer is a critical health issue for women nowadays. Its impact is significant because of its high mortality rate (324,603 worldwide), late-stage diagnosis and poor survival rate. Lack of screening tests, vague symptoms, misdiagnosis, and ag...
Discovery of mutations predictive of survival benefit from immunotherapy in first-line NSCLC: A retrospective machine learning study of IMpower150 liquid biopsy data.
Computers in biology and medicine
Mar 4, 2025
Predictive biomarker identification in cancer treatment has traditionally relied on pre-defined analyses, limiting discoveries to expected biomarkers and potentially overlooking novel ones predictive of therapy response. In this work, we develop a no...
Liquid Biopsy
Clinical Trials, Phase III as Topic
Bevacizumab
Randomized Controlled Trials as Topic
Mutation
Machine Learning
Paclitaxel
Retrospective Studies
Lung Neoplasms
Female
Immunotherapy
Aged
Antineoplastic Combined Chemotherapy Protocols
Humans
Biomarkers, Tumor
Carcinoma, Non-Small-Cell Lung
Male
Middle Aged
Identification of 17 novel epigenetic biomarkers associated with anxiety disorders using differential methylation analysis followed by machine learning-based validation.
Clinical epigenetics
Feb 17, 2025
BACKGROUND: The changes in DNA methylation patterns may reflect both physical and mental well-being, the latter being a relatively unexplored avenue in terms of clinical utility for psychiatric disorders. In this study, our objective was to identify ...
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