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Graft Survival

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Assessing donor kidney function: the role of CIRBP in predicting delayed graft function post-transplant.

Frontiers in immunology
INTRODUCTION: Delayed graft function (DGF) shortens the survival time of transplanted kidneys and increases the risk of rejection. Current methods are inadequate in predicting DGF. More precise tools are required to assess kidney suitability for tran...

Deciphering the impact of senescence in kidney transplant rejection: An integrative machine learning and multi-omics analysis via bulk and single-cell RNA sequencing.

PloS one
BACKGROUND: The demographic shift towards an older population presents significant challenges for kidney transplantation (KTx), particularly due to the vulnerability of aged donor kidneys to ischemic damage, delayed graft function, and reduced graft ...

Predicting graft survival in paediatric kidney transplant recipients using machine learning.

Pediatric nephrology (Berlin, Germany)
BACKGROUND: Identification of factors that affect graft survival in kidney transplantation can increase graft survival and reduce mortality. Artificial intelligence modelling enables impartial evaluation of clinician bias. This study aimed to examine...

Improved survival prediction for kidney transplant outcomes using artificial intelligence-based models: development of the UK Deceased Donor Kidney Transplant Outcome Prediction (UK-DTOP) Tool.

Renal failure
The UK Deceased Donor Kidney Transplant Outcome Prediction (UK-DTOP) Tool, developed using advanced artificial intelligence (AI), significantly enhances the prediction of outcomes for deceased-donor kidney transplants in the UK. This study analyzed d...

Artificial intelligence assisted risk prediction in organ transplantation: a UK Live-Donor Kidney Transplant Outcome Prediction tool.

Renal failure
Predicting the outcome of a kidney transplant involving a living donor advances donor decision-making donors for clinicians and patients. However, the discriminative or calibration capacity of the currently employed models are limited. We set out to...

Advanced prognostic modeling with deep learning: assessing long-term outcomes in liver transplant recipients from deceased and living donors.

Journal of translational medicine
BACKGROUND: Predicting long-term outcomes in liver transplantation remain a challenging endeavor. This research aims to harness the power of deep learning to develop an advanced prognostic model for assessing long-term outcomes, with a specific focus...

Developing clinical prognostic models to predict graft survival after renal transplantation: comparison of statistical and machine learning models.

BMC medical informatics and decision making
INTRODUCTION: Renal transplantation is a critical treatment for end-stage renal disease, but graft failure remains a significant concern. Accurate prediction of graft survival is crucial to identify high-risk patients. This study aimed to develop pro...

Utilizing Machine Learning to Predict Liver Allograft Fibrosis by Leveraging Clinical and Imaging Data.

Clinical transplantation
BACKGROUND AND AIM: Liver transplant (LT) recipients may succumb to graft-related pathologies, contributing to graft fibrosis (GF). Current methods to diagnose GF are limited, ranging from procedural-related complications to low accuracy. With recent...

Artificial intelligence-enhanced interpretation of kidney transplant biopsy: focus on rejection.

Current opinion in organ transplantation
PURPOSE OF REVIEW: The objective of this review is to provide an update on the application of artificial intelligence (AI) for the histological interpretation of kidney transplant biopsies.