Liver lesion segmentation in ultrasound: A benchmark and a baseline network.

Journal: Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Published Date:

Abstract

Accurate liver lesion segmentation in ultrasound is a challenging task due to high speckle noise, ambiguous lesion boundaries, and inhomogeneous intensity distribution inside the lesion regions. This work first collected and annotated a dataset for liver lesion segmentation in ultrasound. In this paper, we propose a novel convolutional neural network to learn dual self-attentive transformer features for boosting liver lesion segmentation by leveraging the complementary information among non-local features encoded at different layers of the transformer architecture. To do so, we devise a dual self-attention refinement (DSR) module to synergistically utilize self-attention and reverse self-attention mechanisms to extract complementary lesion characteristics between cascaded multi-layer feature maps, assisting the model to produce more accurate segmentation results. Moreover, we propose a False-Positive-Negative loss to enable our network to further suppress the non-liver-lesion noise at shallow transformer layers and enhance more target liver lesion details into CNN features at deep transformer layers. Experimental results show that our network outperforms state-of-the-art methods quantitatively and qualitatively.

Authors

  • Jialu Li
    Clinical and Research Center of AIDS, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
  • Lei Zhu
    School of Civil and Hydraulic Engineering, Ningxia University, Yinchuan, China.
  • Guibao Shen
    The Hong Kong University of Science and Technology (Guangzhou), Guangdong, China. Electronic address: gb.shen@siat.ac.cn.
  • Baoliang Zhao
    Shenzhen Key Laboratory of Minimally Invasive Surgical Robotics and System, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences , Shenzhen , China.
  • Ying Hu
    Department of Ultrasonography, The First Affiliated Hospital, College of Medicine, Zhejiang University, Qingchun Road No. 79, Hangzhou, Zhejiang 310003, China.
  • Hai Zhang
    a State Key Laboratory Breeding Base of Systematic Research Development and Utilization of Chinese Medicine Resources, Sichuan Province and Ministry of Science and Technology, College of Pharmacy and College of Ethnic Medicine , Chengdu University of Traditional Chinese Medicine , Chengdu , China.
  • Weiming Wang
    School of Mechanical Engineering, Shanghai Jiao Tong University, Shanghai, China.
  • Qiong Wang
    Beijing Meiling Biotechnology Corporation, Beijing, 102600, PR China.