Development of a chitosanase 3-like protein 1 assay kit and study of its application in patients with hepatocellular carcinoma.

Journal: BMC biotechnology
PMID:

Abstract

OBJECTIVE: The detection kit for plasma Chitinase-3-like Protein 1 was developed using the magnetic bead chemiluminescence method, in order to investigate the diagnostic value of DD, FDP, CHI3L1, AFP-L3 and PIVKA-II in hepatocellular carcinoma.

Authors

  • Min Liu
    Department of Critical Care Medicine, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Wuxi, China.
  • Yanru Qiu
    Department of Laboratory Medicine, Affiliated Hospital of Jiangnan University, No. 1000 Hefeng Road, Wuxi City, Jiangsu Province, 214122, China.
  • Erfu Xie
    Department of Laboratory Medicine, The First Afiliated Hospital with Nanjing Medical University, Nanjing City, Jiangsu, China.
  • Pu Qian
    Department of Laboratory Medicine, Affiliated Hospital of Jiangnan University, No. 1000 Hefeng Road, Wuxi City, Jiangsu Province, 214122, China.
  • Shuxian Yang
    Department of Laboratory Medicine, The First Afiliated Hospital with Nanjing Medical University, Nanjing City, Jiangsu, China.
  • Simin Zhao
    Department of Laboratory Medicine, Affiliated Hospital of Jiangnan University, No. 1000 Hefeng Road, Wuxi City, Jiangsu Province, 214122, China.
  • Wenjun Yan
    Department of Laboratory Medicine, Affiliated Hospital of Jiangnan University, No. 1000 Hefeng Road, Wuxi City, Jiangsu Province, 214122, China.
  • Xuan Huang
    Department of Gastroenterology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
  • Shuang Han
    Department of Pathology, Affiliated Hospital of Jiangnan University, No. 1000 Hefeng Road, Wuxi City, Jiangsu Province, 214122, China. han_frost@163.com.