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Luminescent Measurements

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Bacterial metabolism-triggered-chemiluminescence-based point-of-care testing platform for sensitive detection and photothermal inactivation of Staphylococcus aureus.

Analytica chimica acta
Post-operative pathogenic infections in liver transplantation seriously threaten human health. It is essential to develop novel methods for the highly sensitive and rapid detection of Staphylococcus aureus (S. aureus). Interestingly, the combination ...

Aggregation-induced electrochemiluminescence enhancement of Ag-MOG for amyloid β 42 sensing.

Analytica chimica acta
This study aimed to introduce an immunosensor for measuring amyloid β 42 (Aβ) levels by aggregation-induced enhanced electrochemiluminescence (ECL). Metal-organic gels (MOGs) are novel soft materials with advantages such as high gel stability, good l...

Development of a chitosanase 3-like protein 1 assay kit and study of its application in patients with hepatocellular carcinoma.

BMC biotechnology
OBJECTIVE: The detection kit for plasma Chitinase-3-like Protein 1 was developed using the magnetic bead chemiluminescence method, in order to investigate the diagnostic value of DD, FDP, CHI3L1, AFP-L3 and PIVKA-II in hepatocellular carcinoma.

Persistent Luminescence Lifetime-Based Near-Infrared Nanoplatform via Deep Learning for High-Fidelity Biosensing of Hypochlorite.

Analytical chemistry
In light of deep tissue penetration and ultralow background, near-infrared (NIR) persistent luminescence (PersL) bioprobes have become powerful tools for bioapplications. However, the inhomogeneous signal attenuation may significantly limit its appli...

Insertable Glucose Sensor Using a Compact and Cost-Effective Phosphorescence Lifetime Imager and Machine Learning.

ACS nano
Optical continuous glucose monitoring (CGM) systems are emerging for personalized glucose management owing to their lower cost and prolonged durability compared to conventional electrochemical CGMs. Here, we report a computational CGM system, which i...

ECLStat: A robust machine learning based visual imaging tool for electrochemiluminescence biosensing.

Computers in biology and medicine
Visual electrochemiluminescence (ECL) has emerged as a prominent diagnostic method for accurately quantifying various disease markers even at point of care setting with high sensitivity and accuracy. It does not employ complicated instruments such as...

Using Machine Learning to Design a FeMOF Bidirectional Regulator for Electrochemiluminescence Sensing of Tau Protein.

ACS applied materials & interfaces
The single-luminophore-based ratiometric electrochemiluminescence (ECL) sensor coupling bidirectional regulator has become a research hotspot in the detection field because of its simplicity and accuracy. However, the limited bidirectional regulator ...

A machine-learning-integrated portable electrochemiluminescence sensing platform for the visualization and high-throughput immunoassays.

Talanta
Electrochemiluminescence (ECL)-based point-of-care testing (POCT) has the potential to facilitate the rapid identification of diseases, offering advantages such as high sensitivity, strong selectivity, and minimal background interference. However, as...

Electrically Driven, Bioluminescent Compliant Devices for Soft Robotics.

ACS applied materials & interfaces
Soft robotics, a research field wherein robots are fabricated from compliant materials, has sparked widespread research interest because of its potential applications in a variety of scenarios. In soft robots, luminescence is an important functionali...

Deep Learning-Enhanced Chemiluminescence Vertical Flow Assay for High-Sensitivity Cardiac Troponin I Testing.

Small (Weinheim an der Bergstrasse, Germany)
Democratizing biomarker testing at the point-of-care requires innovations that match laboratory-grade sensitivity and precision in an accessible format. Here, high-sensitivity detection of cardiac troponin I (cTnI) is demonstrated through innovations...