The latest advances with natural products in drug discovery and opportunities for the future: a 2025 update.

Journal: Expert opinion on drug discovery
Published Date: Jun 5, 2025

Abstract

INTRODUCTION: The landscape of drug discovery is rapidly evolving, with natural products (NPs) playing a pivotal role in the development of novel therapeutics. Despite their historical significance, challenges persist in fully harnessing their potential in the development of modern medicine.

Authors

  • Shaowen Xie
    Department of Spatial Information and Resources Environment, School of Architecture and Planning, Foshan University, Guangdong, Foshan, 528000, China.
  • Fangyi Zhan
    Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing, Jiangsu, China.
  • Jingjie Zhu
    Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing, Jiangsu, China.
  • Shengtao Xu
    Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing, Jiangsu, China.
  • Jinyi Xu
    State Key Laboratory of Natural Medicines and Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing, China.

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