Identification of key genes as diagnostic biomarkers for IBD using bioinformatics and machine learning.

Journal: Journal of translational medicine
Published Date: Jul 3, 2025

Abstract

BACKGROUND: The pathogenesis of inflammatory bowel disease (IBD) involves complex molecular mechanisms, and achieving clinical remission remains challenging. This study aims to identify IBD-potential biomarkers, analyze their correlation with immune cell infiltration, and identify genes that have a causal relationship with IBD.

Authors

  • Tianhao Li
    Tianjin Union Medical Center, Tianjin Medical University, Tianjin, China.
  • Haoren Jing
    Department of Colorectal Surgery, Tianjin Union Medical Center, Tianjin, China.
  • Xinyu Gao
    Department of Colorectal Surgery, Tianjin Union Medical Center, The First Affiliated Hospital of Nankai University, Tianjin, China; Tianjin Institute of Coloproctology, Tianjin, China.
  • Te Zhang
    Department of Thoracic Surgery, Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, Nanjing, China.
  • Haitao Yao
    Department of Colorectal Surgery, Tianjin Union Medical Center, The First Affiliated Hospital of Nankai University, Tianjin, 300121, 2755-7131, China.
  • Xipeng Zhang
    Department of Colorectal Surgery, Tianjin Union Medical Center, Tianjin, China.
  • Mingqing Zhang
    Department of Colorectal Surgery, Tianjin Union Medical Center, Tianjin, China.

Keywords

External Resources

Popular Topics
Recent Journals