Diagnosing facial synkinesis using artificial intelligence to advance facial palsy care.

Journal: Scientific reports
Published Date:

Abstract

Facial palsy (FP) can lead to significant psychological and physical burdens such as facial synkinesis. This involuntary simultaneous movement of facial musculature remains challenging to diagnose and treat. This study aimed to develop a cost-effective, rapid, and accurate artificial intelligence (AI)-based algorithm to screen FP patients for facial synkinesis. Data from 70 FP patients were collected at the University Hospital Regensburg and compared to healthy controls from an online platform. The standardized patient image series included 9 images, of which 3 were used to train the algorithm. The control images were single images. A total of 385 images were used to train and evaluate a convolutional neural network (CNN). The dataset was divided into training (285 images), validation (29 images), and test sets (71 images). The model was trained over 18 epochs. A web application was developed for practical use. The model achieved an accuracy of 98.6% on the test set, correctly identifying 31 of 32 synkinesis cases and all 39 images of healthy individuals. Performance metrics included an F1-score of 98.4%, precision of 100%, and recall of 96.9%. The web application allowed for image upload and rapid synkinesis prediction. The CNN-based model demonstrated high accuracy in detecting synkinesis in FP patients, offering potential for improved diagnostic accuracy and expedited treatment. Further validation with larger datasets is necessary to ensure robustness and generalizability.

Authors

  • Leonard Knoedler
    Department of Plastic, Hand- and Reconstructive Surgery, University Hospital Regensburg, Regensburg, Germany.
  • Christian Festbaum
    Department of Plastic, Hand and Reconstructive Surgery, Hospital Ingolstadt, Ingolstadt, Germany.
  • Jillian Dean
    School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
  • Helena Baecher
    Department of Oral and Maxillofacial Surgery, University Hospital Regensburg, Regensburg, Germany.
  • Grégoire de Lambertye
    Department of Informatics, Vienna Technical University, Vienna, Austria.
  • Maximilian Maul
    Department of Informatics, Vienna Technical University, Vienna, Austria.
  • Thomas Schaschinger
    Department of Oral and Maxillofacial Surgery, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Charité - Universitätsmedizin Berlin, Augustenburger Platz 1, Berlin, Germany.
  • Tobias Niederegger
    Department of Oral and Maxillofacial Surgery, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Charité - Universitätsmedizin Berlin, Augustenburger Platz 1, Berlin, Germany.
  • Alexandra Scheiflinger
    Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • Michael Alfertshofer
    Division of Hand, Plastic and Aesthetic Surgery, Ludwig-Maximilians University Munich, Munich, Germany.
  • Khalil Sherwani
    Medical University of Vienna, Vienna, Austria.
  • Claudius Steffen
    Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Oral and Maxillofacial Surgery, Berlin, Germany.
  • Max Heiland
    Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Oral and Maxillofacial Surgery, Berlin, Germany.
  • Steffen Koerdt
    Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Oral and Maxillofacial Surgery, Berlin, Germany.
  • Samuel Knoedler
    Division of Plastic Surgery, Department of Surgery, Yale New Haven Hospital, Yale School of Medicine, New Haven, CT, United States.
  • Andreas Kehrer
    Department of Plastic, Hand and Reconstructive Surgery, University Hospital Regensburg, Regensburg, Germany.