Evaluating the impact of human expertise in human-centered AI: A case study on finger-tapping video analysis for dementia detection.

Journal: Computers in biology and medicine
Published Date: Jun 2, 2025

Abstract

PURPOSE: Human-centered artificial intelligence (AI) plays a crucial role in medical research. This paper evaluates the impact of human expertise in AI systems, using dementia prediction as a case study. Specifically, plasma phospho-tau181 (ptau181) is employed as the ground truth for Alzheimer's disease (AD) to advance early detection and treatment strategies.

Authors

  • Renjie Li
    College of Geography and Environmental Sciences, Zhejiang Normal University, Jinhua 321004, China.
  • Guan Huang
    School of Education, China West Normal University, Nanchong, Sichuan, China.
  • Yanyu Chen
    ProNet Biotech Co. ltd, Nanjing 210033, China.
  • Xinyi Wang
    School of Biological Sciences & Medical Engineering, Southeast University, Nanjing, China.
  • Jane Alty
    Department of Neurology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
  • Quan Bai
    School of ICT, University of Tasmania, Hobart, Tasmania, 7005, Australia.

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