Ferroptosis-related hub genes and immune cell dynamics as diagnostic biomarkers in age-related macular degeneration.

Journal: European journal of medical research
Published Date: Aug 20, 2025

Abstract

BACKGROUND: Age-related Macular Degeneration (AMD) is widely acknowledged as a principal cause of vision loss in the elderly. Currently, the therapeutic interventions available in clinical practice fail to achieve satisfactory outcomes. Therefore, it is imperative that we approach the progress of AMD from novel perspectives in order to explore new therapeutic strategies.

Authors

  • Jinquan Chen
    Department of Mechanical and Electrical Engineering, Jiangsu Food & Pharmaceutical Science College, Huai'an, China.
  • Zhao Long
    Department of Ophthalmology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Dandan Shi
    Department of Ophthalmology, The People's Hospital of Tongnan District Chongqing City, Chongqing, China.
  • Qian Zhang
    The Neonatal Intensive Care Unit, Peking Union Medical College Hospital, Peking, China.
  • H Peng
    Department of Ophthalmology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. pengh9@sina.com.

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