The predictive value of heparin-binding protein for bacterial infections in patients with severe polytrauma.

Journal: PloS one
PMID: 39724075

Abstract

INTRODUCTION: Heparin-binding protein is an inflammatory factor with predictive value for sepsis and participates in the inflammatory response through antibacterial effects, chemotaxis, and increased vascular permeability. The role of heparin-binding protein in sepsis has been progressively demonstrated, but few studies have been conducted in the context of polytrauma combined with bacterial infections. This study aims to investigate the predictive value of heparin-binding protein for bacterial infections in patients with severe polytrauma.

Authors

  • Li Li
    Department of Gastric Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, Affiliated Cancer Hospital of University of Electronic Science and Technology of China, Chengdu, China.
  • Xiao-Xi Tian
    Department of Emergency, The First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
  • Gui-Long Feng
    Department of Emergency, The First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
  • Bing Chen
    Department of Critical Care Medicine, The Second Hospital of Tianjin Medical University, Tianjin, China.

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