International external validation of the SORG machine learning algorithm for predicting sustained postoperative opioid prescription after anterior cervical discectomy and fusion using a Taiwanese cohort of 1,037 patients.

Journal: The spine journal : official journal of the North American Spine Society
Published Date: Mar 28, 2025

Abstract

BACKGROUND CONTEXT: Anterior cervical discectomy and fusion (ACDF) is widely performed for cervical spine disorders, with opioids commonly prescribed postoperatively for pain management. However, prolonged opioid use carries significant risks such as dependency and adverse health effects. Predictive models like the SORG machine learning algorithm (SORG-MLA) have been developed to forecast prolonged opioid use post-ACDF. External validation is essential to ensure their effectiveness across different healthcare settings and populations.

Authors

  • Yu-Yung Chen
    Department of Orthopaedic Surgery, National Taiwan University Hospital, Taipei City, Taiwan; Department of Medical Education, National Taiwan University Hospital, Taipei City, Taiwan.
  • Hung-Kuan Yen
    School of Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.
  • Jui-Yo Hsu
    Department of Orthopaedic Surgery, National Taiwan University Hospital, Taipei City, Taiwan; Department of Orthopaedic Surgery, National Taiwan University Hospital, Hsin-Chu Branch, Hsin-Chu City, Taiwan.
  • Ta-Chun Lin
    Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Hao-Chen Lin
    Department of Medical Education, National Taiwan University Hospital, Taipei City, Taiwan.
  • Chih-Wei Chen
    Graduate Institute of Biomedical Informatics, College of Medical Science and Technology, Taipei Medical University, Taiwan.
  • Ming-Hsiao Hu
    Department of Orthopedics, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei, Taiwan. Electronic address: minghsiaohu@yahoo.com.tw.
  • Olivier Q Groot
    Department of Orthopedic Surgery, Massachusetts General Hospital, Harvard Medical School, 55 Fruit St, Boston, MA 02114, USA.
  • Joseph H Schwab
    Department of Orthopedic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA. Electronic address: jhschwab@mgh.harvard.edu.

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