Current State of Evidence for Use of MRI in LI-RADS.

Journal: Journal of magnetic resonance imaging : JMRI
Published Date: Feb 21, 2025

Abstract

The American College of Radiology Liver Imaging Reporting and Data System (LI-RADS) is the preeminent framework for classification and risk stratification of liver observations on imaging in patients at high risk for hepatocellular carcinoma. In this review, the pathogenesis of hepatocellular carcinoma and the use of MRI in LI-RADS is discussed, including specifically the LI-RADS diagnostic algorithm, its components, and its reproducibility with reference to the latest supporting evidence. The LI-RADS treatment response algorithms are reviewed, including the more recent radiation treatment response algorithm. The application of artificial intelligence, points of controversy, LI-RADS relative to other liver imaging systems, and possible future directions are explored. After reading this article, the reader will have an understanding of the foundation and application of LI-RADS as well as possible future directions.

Authors

  • Ameya Madhav Kulkarni
    Department of Medical Imaging, Hamilton Health Sciences, McMaster University, Hamilton, Ontario, Canada.
  • Danielle Kruse
    Departments of Radiology and Medicine, Duke University Medical Center, Durham, North Carolina, USA.
  • Kelly Harper
    Department of Radiology, The Ottawa Hospital, University of Ottawa, Ottawa, Ontario, Canada.
  • Eric Lam
    Ottawa Hospital Research Institute Clinical Epidemiology Program, Ottawa, Ontario, Canada.
  • Hoda Osman
    Ottawa Hospital Research Institute Clinical Epidemiology Program, Ottawa, Ontario, Canada.
  • Danyaal H Ansari
    Ottawa Hospital Research Institute Clinical Epidemiology Program, Ottawa, Ontario, Canada.
  • Umaseh Sivanesan
    Department of Diagnostic Radiology, Kingston Health Sciences Centre, Kingston General Hospital, Kingston, Ontario, Canada.
  • Mustafa R Bashir
    Department of Radiology, Duke University, Durham, North Carolina, USA.
  • Andreu F Costa
    Department of Diagnostic Radiology, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Victoria General Building, 3rd Floor, 1276 South Park Street, Halifax, NS, B3H 2Y9, Canada.
  • Matthew McInnes
    Department of Radiology, University of Ottawa, Ottawa, Ontario, Canada.
  • Christian B van der Pol
    Department of Radiology, McMaster University, Hamilton, Ontario, Canada.

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