Development of a compact continuum tubular robotic system for nasopharyngeal biopsy.

Journal: Medical & biological engineering & computing
Published Date:

Abstract

Traditional posterior nasopharyngeal biopsy using a flexible nasal endoscope has the risks of abrasion and injury to the nasal mucosa and thus causing trauma to the patient. Recently, a new class of robots known as continuum tubular robots (CTRs) provide a novel solution to the challenge with miniaturized size, curvilinear maneuverability, and capability of avoiding collision within the nasal environment. This paper presents a compact CTR which is 35 cm in total length, 10 cm in diameter, 2.15 kg in weight, and easy to be integrated with a robotic arm to perform more complicated operations. Structural design, end-effector design, and workspace analysis are described in detail. In addition, teleoperation of the CTR using a haptic input device is developed for position control in 3D space. Moreover, by integrating the robot with three electromagnetic tracking sensors, a navigation system together with a shape reconstruction algorithm is developed. Comprehensive experiments are conducted to test the functionality of the proposed prototype; experiment results show that under teleoperation, the system has an accuracy of 2.20 mm in following a linear path, an accuracy of 2.01 mm in following a circular path, and a latency time of 0.1 s. It is also found that the proposed shape reconstruction algorithm has a mean error of around 1 mm along the length of the tubes. Besides, the feasibility and effectiveness of the proposed robotic system being applied to posterior nasopharyngeal biopsy are demonstrated by a cadaver experiment. The proposed robotic system holds promise to enhance clinical operation in transnasal procedures.

Authors

  • Liao Wu
    School of Electrical Engineering and Computer Science, Queensland University of Technology, Brisbane, Australia.
  • Shuang Song
    Department of Ophthalmology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.
  • Keyu Wu
    Department of Biomedical Engineering, National University of Singapore, Singapore, Singapore.
  • Chwee Ming Lim
    Department of Otolaryngology-Head and Neck Surgery, National University Hospital, Singapore, Singapore.
  • Hongliang Ren
    Department of Biomedical Engineering, National University of Singapore, Singapore, Singapore. ren@nus.edu.sg.