Network or regression-based methods for disease discrimination: a comparison study.

Journal: BMC medical research methodology
Published Date: Aug 18, 2016

Abstract

BACKGROUND: In stark contrast to network-centric view for complex disease, regression-based methods are preferred in disease prediction, especially for epidemiologists and clinical professionals. It remains a controversy whether the network-based methods have advantageous performance than regression-based methods, and to what extent do they outperform.

Authors

  • Xiaoshuai Zhang
    Department of Epidemiology and Biostatistics, School of Public Health, Shandong University, PO Box 100, Jinan, 250012, China.
  • Zhongshang Yuan
    Department of Epidemiology and Biostatistics, School of Public Health, Shandong University, PO Box 100, Jinan, 250012, China.
  • Jiadong Ji
    Department of Epidemiology and Biostatistics, School of Public Health, Shandong University, PO Box 100, Jinan, 250012, China.
  • Hongkai Li
    Department of Epidemiology and Biostatistics, School of Public Health, Shandong University, PO Box 100, Jinan, 250012, China.
  • Fuzhong Xue
    Department of Epidemiology and Biostatistics, School of Public Health, Shandong University, PO Box 100, Jinan, 250012, China. xuefzh@sdu.edu.cn.

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