Evaluation of the cytotoxic effect of titanium dioxide nanoparticles in human embryonic lung cells.

Journal: Turkish journal of medical sciences
PMID:

Abstract

BACKGROUND/AIM: Titanium dioxide nanoparticles are widely used in a variety of products, including sunscreens, paints, and ceramics. However, their increasing use has raised concerns about their potential health risks. Titanium dioxide nanoparticles have been shown to have the ability to enter the bloodstream and accumulate in various tissues, reaching the fetus via the placenta. The aim of this study was to investigate the cytotoxic effects of titanium dioxide nanoparticles on a human embryonic lung cell line (HEL 299/An1) and the formation of oxidative DNA damage.

Authors

  • Olkan Afşar
    Department of Pharmaceutical Nanotechnology, Institute of Health Sciences, Trakya University, Edirne, Turkiye.
  • Çağatay Oltulu
    Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Trakya University, Edirne, Turkiye.