Quantitative noninvasive measurement of cerebrospinal fluid flow in shunted hydrocephalus.

Journal: Journal of neurosurgery
PMID:

Abstract

OBJECTIVE: Standard MRI protocols lack a quantitative sequence that can be used to evaluate shunt-treated patients with a history of hydrocephalus. The objective of this study was to investigate the use of phase-contrast MRI (PC-MRI), a quantitative MR sequence, to measure CSF flow through the shunt and demonstrate PC-MRI as a useful adjunct in the clinical monitoring of shunt-treated patients.

Authors

  • Joseph H Ha
    1Division of Neurosurgery, Children's Hospital Los Angeles.
  • Matthew T Borzage
    2Department of Pediatrics, Division of Neonatology, Fetal and Neonatal Institute, Children's Hospital Los Angeles.
  • Erik B Vanstrum
    3Department of Head and Neck Surgery, David Geffen School of Medicine at the University of California, Los Angeles.
  • Eamon K Doyle
    4Department of Radiology, Children's Hospital Los Angeles.
  • Meenakshi Upreti
    1Division of Neurosurgery, Children's Hospital Los Angeles.
  • Benita Tamrazi
    4Department of Radiology, Children's Hospital Los Angeles.
  • Marvin Nelson
    4Department of Radiology, Children's Hospital Los Angeles.
  • Stefan Blüml
    4Department of Radiology, Children's Hospital Los Angeles.
  • Malkiat S Johal
    5Department of Chemistry, Pomona College, Claremont.
  • J Gordon McComb
    1Division of Neurosurgery, Children's Hospital Los Angeles.
  • Jason Chu
    1Division of Neurosurgery, Children's Hospital Los Angeles.
  • Susan Durham
    1Division of Neurosurgery, Children's Hospital Los Angeles.
  • Mark D Krieger
    1Division of Neurosurgery, Children's Hospital Los Angeles.
  • Rex A Moats
    6The Saban Research Institute, Children's Hospital Los Angeles; and.
  • Peter A Chiarelli
    1Division of Neurosurgery, Children's Hospital Los Angeles.