Tonic regulation of stationary asynchronous firing of a neural network.
Journal:
Journal of computational neuroscience
Published Date:
Oct 1, 2017
Abstract
The impact of tonic conductance upon population activity was investigated. An extra tonic transmembrane current through GABA-activated extrasynaptic GABA -receptors was found to control stationary asynchronous firing both quantitatively and qualitatively. Quantitative regulation consisted in alterating a current level of stationary population activity while qualitative regulation manifested itself in appearance of resilient asynchronous spiking in case GABA reversal potential exceeded a certain threshold. The study was based on a modified rate model after Wilson and Cowan and backed up with a computer simulation of an explicit network model.