Machine-learning phenotypic classification of bicuspid aortopathy.

Journal: The Journal of thoracic and cardiovascular surgery
PMID:

Abstract

BACKGROUND: Bicuspid aortic valves (BAV) are associated with incompletely characterized aortopathy. Our objectives were to identify distinct patterns of aortopathy using machine-learning methods and characterize their association with valve morphology and patient characteristics.

Authors

  • Charles M Wojnarski
    Department of Thoracic and Cardiovascular Surgery, Miller Family Heart and Vascular Institute, Cleveland, Ohio.
  • Eric E Roselli
    Department of Thoracic and Cardiovascular Surgery, Miller Family Heart and Vascular Institute, Cleveland, Ohio; Aortic Center, Miller Family Heart and Vascular Institute, Cleveland, Ohio. Electronic address: roselle@ccf.org.
  • Jay J Idrees
    Department of Thoracic and Cardiovascular Surgery, Miller Family Heart and Vascular Institute, Cleveland, Ohio.
  • Yuanjia Zhu
    Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio.
  • Theresa A Carnes
    Department of Quantitative Health Sciences, Research Institute, Cleveland Clinic, Cleveland, Ohio.
  • Ashley M Lowry
    Department of Quantitative Health Sciences, Research Institute, Cleveland Clinic, Cleveland, Ohio.
  • Patrick H Collier
    Aortic Center, Miller Family Heart and Vascular Institute, Cleveland, Ohio; Department of Cardiovascular Medicine, Miller Family Heart and Vascular Institute, Cleveland, Ohio.
  • Brian Griffin
    Aortic Center, Miller Family Heart and Vascular Institute, Cleveland, Ohio; Department of Cardiovascular Medicine, Miller Family Heart and Vascular Institute, Cleveland, Ohio.
  • John Ehrlinger
    Department of Quantitative Health Sciences, Cleveland Clinic.
  • Eugene H Blackstone
    Department of Heart and Vascular Institute, Cleveland Clinic.
  • Lars G Svensson
    Department of Thoracic and Cardiovascular Surgery, Miller Family Heart and Vascular Institute, Cleveland, Ohio; Aortic Center, Miller Family Heart and Vascular Institute, Cleveland, Ohio.
  • Bruce W Lytle
    Department of Thoracic and Cardiovascular Surgery, Miller Family Heart and Vascular Institute, Cleveland, Ohio.