Deep learning in mammography and breast histology, an overview and future trends.

Journal: Medical image analysis
Published Date:

Abstract

Recent improvements in biomedical image analysis using deep learning based neural networks could be exploited to enhance the performance of Computer Aided Diagnosis (CAD) systems. Considering the importance of breast cancer worldwide and the promising results reported by deep learning based methods in breast imaging, an overview of the recent state-of-the-art deep learning based CAD systems developed for mammography and breast histopathology images is presented. In this study, the relationship between mammography and histopathology phenotypes is described, which takes biological aspects into account. We propose a computer based breast cancer modelling approach: the Mammography-Histology-Phenotype-Linking-Model, which develops a mapping of features/phenotypes between mammographic abnormalities and their histopathological representation. Challenges are discussed along with the potential contribution of such a system to clinical decision making and treatment management.

Authors

  • Azam Hamidinekoo
    Department of Computer Science, Aberystwyth University, United Kingdom. Electronic address: azh2@aber.ac.uk.
  • Erika Denton
    Department of Radiology, Norfolk and Norwich University Hospital, United Kingdom. Electronic address: erika.denton@nnuh.nhs.uk.
  • Andrik Rampun
    School of Computing, Ulster University, Coleraine, Northern Ireland, United Kingdom. Electronic address: y.rampun@ulster.ac.uk.
  • Kate Honnor
    Department of Histopathology/Cytopathology, Norfolk and Norwich University Hospital, United Kingdom. Electronic address: kate.honnor@nnuh.nhs.uk.
  • Reyer Zwiggelaar
    Department of Computer Science, Aberystwyth University, Ceredigion, United Kingdom.