Automated detection of focal cortical dysplasia type II with surface-based magnetic resonance imaging postprocessing and machine learning.

Journal: Epilepsia
PMID: 29637549

Abstract

OBJECTIVE: Focal cortical dysplasia (FCD) is a major pathology in patients undergoing surgical resection to treat pharmacoresistant epilepsy. Magnetic resonance imaging (MRI) postprocessing methods may provide essential help for detection of FCD. In this study, we utilized surface-based MRI morphometry and machine learning for automated lesion detection in a mixed cohort of patients with FCD type II from 3 different epilepsy centers.

Authors

  • Bo Jin
    HBISolutions Inc., Palo Alto, CA 94301, USA.
  • Balu Krishnan
    Epilepsy Center, Cleveland Clinic, Cleveland, OH, USA.
  • Sophie Adler
    Developmental Neurosciences, UCL Great Ormond Street Institute of Child Health, University College London, London, UK.
  • Konrad Wagstyl
    Developmental Neurosciences, UCL Great Ormond Street Institute of Child Health, University College London, London, UK.
  • Wenhan Hu
    Department of Neurosurgery, Beijing Neurosurgical Institute, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
  • Stephen Jones
    Imaging Institute, Cleveland Clinic, Cleveland, OH, USA.
  • Imad Najm
    Epilepsy Center, Cleveland Clinic, Cleveland, OH, USA.
  • Andreas Alexopoulos
    Epilepsy Center, Cleveland Clinic, Cleveland, OH, USA.
  • Kai Zhang
    Anhui Province Key Laboratory of Respiratory Tumor and Infectious Disease, First Affiliated Hospital of Bengbu Medical University, Bengbu, China.
  • Jianguo Zhang
    College of Automation, Harbin Engineering University, No. 145, Nantong street, Harbin, China.
  • Meiping Ding
    Department of Neurology, School of Medicine, Epilepsy Center, Second Affiliated Hospital, Zhejiang University, Hangzhou, China.
  • Shuang Wang
    Engineering Technology Research Center of Shanxi Province for Opto-Electric Information and Instrument, Taiyuan 030051, China. S1507038@st.nuc.edu.cn.
  • Zhong Irene Wang
    Epilepsy Center, Cleveland Clinic, Cleveland, OH, USA.

Keywords

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