Automatic Determination of the Need for Intravenous Contrast in Musculoskeletal MRI Examinations Using IBM Watson's Natural Language Processing Algorithm.

Journal: Journal of digital imaging
PMID:

Abstract

Magnetic resonance imaging (MRI) protocoling can be time- and resource-intensive, and protocols can often be suboptimal dependent upon the expertise or preferences of the protocoling radiologist. Providing a best-practice recommendation for an MRI protocol has the potential to improve efficiency and decrease the likelihood of a suboptimal or erroneous study. The goal of this study was to develop and validate a machine learning-based natural language classifier that can automatically assign the use of intravenous contrast for musculoskeletal MRI protocols based upon the free-text clinical indication of the study, thereby improving efficiency of the protocoling radiologist and potentially decreasing errors. We utilized a deep learning-based natural language classification system from IBM Watson, a question-answering supercomputer that gained fame after challenging the best human players on Jeopardy! in 2011. We compared this solution to a series of traditional machine learning-based natural language processing techniques that utilize a term-document frequency matrix. Each classifier was trained with 1240 MRI protocols plus their respective clinical indications and validated with a test set of 280. Ground truth of contrast assignment was obtained from the clinical record. For evaluation of inter-reader agreement, a blinded second reader radiologist analyzed all cases and determined contrast assignment based on only the free-text clinical indication. In the test set, Watson demonstrated overall accuracy of 83.2% when compared to the original protocol. This was similar to the overall accuracy of 80.2% achieved by an ensemble of eight traditional machine learning algorithms based on a term-document matrix. When compared to the second reader's contrast assignment, Watson achieved 88.6% agreement. When evaluating only the subset of cases where the original protocol and second reader were concordant (n = 251), agreement climbed further to 90.0%. The classifier was relatively robust to spelling and grammatical errors, which were frequent. Implementation of this automated MR contrast determination system as a clinical decision support tool may save considerable time and effort of the radiologist while potentially decreasing error rates, and require no change in order entry or workflow.

Authors

  • Hari Trivedi
    Department of Radiology, Medical College of Georgia at Augusta University, 1120 15th St, Augusta, GA 30912 (Y.T.); and Department of Radiology, Emory University, Atlanta, Ga (B.V., E.K., A.P., J.G., N.S., H.T.).
  • Joseph Mesterhazy
    From the Department of Radiology, Medical University of South Carolina, 96 Jonathan Lucas St, Charleston, SC 29425-3230 (M.D.K.); Department of Radiology and Biomedical Imaging, University of California, San Francisco, Calif (J. Mesterhazy, D.A., J. Mongan); and The Permanente Medical Group, Oakland, Calif (T.U.).
  • Benjamin Laguna
    Radiology & Biomedical Imaging, UCSF Medical Center, 505 Parnassus Ave, San Francisco, CA, 94158, USA.
  • Thienkhai Vu
    Radiology & Biomedical Imaging, UCSF Medical Center, 505 Parnassus Ave, San Francisco, CA, 94158, USA.
  • Jae Ho Sohn
    Radiology & Biomedical Imaging, UCSF Medical Center, 505 Parnassus Ave, San Francisco, CA, 94158, USA. sohn87@gmail.com.