IGF-1 stabilizes goat sperm mitochondrial transmembrane potential and reduces dna fragmentation.

Journal: Cryo letters
PMID: 38311926

Abstract

BACKGROUND: Antioxidant present in sperm cells protects them from oxidative damage. However, sperm are more susceptible to peroxidative damages due to the loss of these enzymes during cryopreservation and their survival and fertility may be compromised. Insulin like growth factor-1 (IGF-1) has an antioxidant effect and could maintain sperm motility.

Authors

  • R Ranjan
    Indian Council of Agricultural Research (ICAR), Central Institute for Research on Goats, Makhdoom, Farah, Mathura, Uttar Pradesh (U.P.), India. dr_raviranjan@yahoo.co.in.
  • K Sharma
    Indian Council of Agricultural Research (ICAR), Central Institute for Research on Goats, Makhdoom, Farah, Mathura, Uttar Pradesh (U.P.), India.
  • M Kumar
    Indian Council of Agricultural Research (ICAR), Central Institute for Research on Goats, Makhdoom, Farah, Mathura, Uttar Pradesh (U.P.), India.
  • D K Swain
    Deen Dayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalaya Evam Go-Anusandhan Sansthan (DUVASU), Mathura, U.P. India.
  • S P Singh
    Indian Council of Agricultural Research (ICAR), Central Institute for Research on Goats, Makhdoom, Farah, Mathura, Uttar Pradesh (U.P.), India.
  • S D Kharche
    Indian Council of Agricultural Research (ICAR), Central Institute for Research on Goats, Makhdoom, Farah, Mathura, Uttar Pradesh (U.P.), India.
  • M K Singh
    Indian Council of Agricultural Research (ICAR), Central Institute for Research on Goats, Makhdoom, Farah, Mathura, Uttar Pradesh (U.P.), India.
  • M S Chauhan
    ICAR-National Dairy Research Institute, Karnal, Haryana, India.

Keywords

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