Deep learning based low-cost high-accuracy diagnostic framework for dementia using comprehensive neuropsychological assessment profiles.

Journal: BMC geriatrics
PMID: 30285646

Abstract

BACKGROUND: The conventional scores of the neuropsychological batteries are not fully optimized for diagnosing dementia despite their variety and abundance of information. To achieve low-cost high-accuracy diagnose performance for dementia using a neuropsychological battery, a novel framework is proposed using the response profiles of 2666 cognitively normal elderly individuals and 435 dementia patients who have participated in the Korean Longitudinal Study on Cognitive Aging and Dementia (KLOSCAD).

Authors

  • Hyun-Soo Choi
    Department of Electrical and Computer Engineering, Seoul National University, room 908 Bldg. 301, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, Korea.
  • Jin Yeong Choe
    Department of Brain and Cognitive Sciences, Seoul National University College of Natural Sciences, Seoul, Korea.
  • Hanjoo Kim
    Department of Electrical and Computer Engineering, Seoul National University, room 908 Bldg. 301, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, Korea.
  • Ji Won Han
    Department of Neuropsychiatry, Seoul National University Bundang Hospital, 82 Gumi-ro 173beon-gil, Bundang-gu, Gyeonggi, 13620, Korea.
  • Yeon Kyung Chi
    Department of Neuropsychiatry, Seoul National University Bundang Hospital, 82 Gumi-ro 173beon-gil, Bundang-gu, Gyeonggi, 13620, Korea.
  • Kayoung Kim
    Department of Neuropsychiatry, Seoul National University Bundang Hospital, 82 Gumi-ro 173beon-gil, Bundang-gu, Gyeonggi, 13620, Korea.
  • Jongwoo Hong
    School of Mechanical Engineering, Yonsei University, 50, Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.
  • Taehyun Kim
    Department of Neuropsychiatry, Seoul National University Bundang Hospital, 82 Gumi-ro 173beon-gil, Bundang-gu, Gyeonggi, 13620, Korea.
  • Tae Hui Kim
    Department of Psychiatry, Yonsei University Wonju Severance Christian Hospital, Wonju, Korea.
  • Sungroh Yoon
    4 Department of Electrical and Computer Engineering and Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul, Korea.
  • Ki Woong Kim
    Department of Brain and Cognitive Sciences, Seoul National University College of Natural Sciences, Seoul, Korea. kwkimmd@snu.ac.kr.

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