A machine learning algorithm predicts molecular subtypes in pancreatic ductal adenocarcinoma with differential response to gemcitabine-based versus FOLFIRINOX chemotherapy.
Journal:
PloS one
PMID:
31577805
Abstract
PURPOSE: Development of a supervised machine-learning model capable of predicting clinically relevant molecular subtypes of pancreatic ductal adenocarcinoma (PDAC) from diffusion-weighted-imaging-derived radiomic features.
Authors
Keywords
Adult
Antineoplastic Combined Chemotherapy Protocols
Carcinoma, Pancreatic Ductal
Deoxycytidine
Disease-Free Survival
Female
Fluorouracil
Gemcitabine
Humans
Irinotecan
Keratins, Hair-Specific
Keratins, Type II
Leucovorin
Machine Learning
Male
Middle Aged
Neoplasm Proteins
Oxaliplatin
Pancreatic Neoplasms
Retrospective Studies
Sensitivity and Specificity
Survival Rate