AIMC Topic: Leucovorin

Clear Filters Showing 1 to 6 of 6 articles

Machine Learning Predicts Oxaliplatin Benefit in Early Colon Cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology Feb 5, 2024
PURPOSE: A combination of fluorouracil, leucovorin, and oxaliplatin (FOLFOX) is the standard for adjuvant therapy of resected early-stage colon cancer (CC). Oxaliplatin leads to lasting and disabling neurotoxicity. Reserving the regimen for patients ...
Female Aged Adult Male Humans Machine Learning Chemotherapy, Adjuvant Clinical Trials, Phase III as Topic Organoplatinum Compounds Leucovorin Neoplasm Staging Colonic Neoplasms Fluorouracil Middle Aged Antineoplastic Combined Chemotherapy Protocols Oxaliplatin
View on PubMed DOI

FOLFOX treatment response prediction in metastatic or recurrent colorectal cancer patients via machine learning algorithms.

Cancer medicine Jan 1, 2020
Early identification of metastatic or recurrent colorectal cancer (CRC) patients who will be sensitive to FOLFOX (5-FU, leucovorin and oxaliplatin) therapy is very important. We performed microarray meta-analysis to identify differentially expressed ...
Intracellular Signaling Peptides and Proteins Response Evaluation Criteria in Solid Tumors Leucovorin Organoplatinum Compounds Cell Cycle Proteins Oligonucleotide Array Sequence Analysis Fluorouracil Protein Kinases Datasets as Topic Prognosis Colorectal Neoplasms Biomarkers, Tumor Antineoplastic Combined Chemotherapy Protocols Humans Gene Expression Profiling Neoplasm Recurrence, Local Machine Learning Gene Expression Regulation, Neoplastic
View on PubMed DOI

A machine learning algorithm predicts molecular subtypes in pancreatic ductal adenocarcinoma with differential response to gemcitabine-based versus FOLFIRINOX chemotherapy.

PloS one Oct 2, 2019
PURPOSE: Development of a supervised machine-learning model capable of predicting clinically relevant molecular subtypes of pancreatic ductal adenocarcinoma (PDAC) from diffusion-weighted-imaging-derived radiomic features.
Disease-Free Survival Deoxycytidine Gemcitabine Neoplasm Proteins Sensitivity and Specificity Fluorouracil Male Middle Aged Carcinoma, Pancreatic Ductal Antineoplastic Combined Chemotherapy Protocols Leucovorin Irinotecan Oxaliplatin Female Pancreatic Neoplasms Keratins, Hair-Specific Adult Humans Keratins, Type II Survival Rate Machine Learning Retrospective Studies
View on PubMed DOI

Prediction of irinotecan toxicity in metastatic colorectal cancer patients based on machine learning models with pharmacokinetic parameters.

Journal of pharmacological sciences May 4, 2019
Irinotecan (CPT-11) is a drug used against a wide variety of tumors, which can cause severe toxicity, possibly leading to the delay or suspension of the cycle, with the consequent impact on the prognosis of survival. The main goal of this work is to ...
Antineoplastic Combined Chemotherapy Protocols Oxaliplatin Models, Biological Camptothecin Topoisomerase I Inhibitors Fluorouracil Leukopenia Male Middle Aged Diarrhea Female Aged Colorectal Neoplasms Neutropenia Irinotecan Humans Leucovorin Machine Learning Glucuronates Forecasting
View on PubMed DOI

Use of Deep Learning to Evaluate Tumor Microenvironmental Features for Prediction of Colon Cancer Recurrence.

Cancer research communications May 23, 2024
UNLABELLED: Deep learning may detect biologically important signals embedded in tumor morphologic features that confer distinct prognoses. Tumor morphologic features were quantified to enhance patient risk stratification within DNA mismatch repair (M...
Middle Aged Deep Learning Antineoplastic Combined Chemotherapy Protocols Aged Tumor Microenvironment Male Fluorouracil Chemotherapy, Adjuvant Organoplatinum Compounds Leucovorin DNA Mismatch Repair Neoplasm Recurrence, Local Colonic Neoplasms Prognosis Female Humans
View on PubMed DOI

[A Case of Locally Advanced Rectal Cancer Treated by Robot Assisted Intersphincteric Resection after Neoadjuvant Chemotherapy].

Gan to kagaku ryoho. Cancer & chemotherapy Jan 1, 2021
We present a case of locally advanced rectal cancer(LARC)treated by robot assisted intersphincteric resection(ISR)and lateral lymph node dissection(LLND)after neoadjuvant chemotherapy(NAC). The patient was a 69-year-old female with the diagnosis of a...
Rectum Fluorouracil Rectal Neoplasms Antineoplastic Combined Chemotherapy Protocols Neoadjuvant Therapy Robotics Leucovorin Humans Female Aged
View on PubMed
Popular Topics
Recent Journals