Deep Learning Applications in Chest Radiography and Computed Tomography: Current State of the Art.

Journal: Journal of thoracic imaging
Published Date:

Abstract

Deep learning is a genre of machine learning that allows computational models to learn representations of data with multiple levels of abstraction using numerous processing layers. A distinctive feature of deep learning, compared with conventional machine learning methods, is that it can generate appropriate models for tasks directly from the raw data, removing the need for human-led feature extraction. Medical images are particularly suited for deep learning applications. Deep learning techniques have already demonstrated high performance in the detection of diabetic retinopathy on fundoscopic images and metastatic breast cancer cells on pathologic images. In radiology, deep learning has the opportunity to provide improved accuracy of image interpretation and diagnosis. Many groups are exploring the possibility of using deep learning-based applications to solve unmet clinical needs. In chest imaging, there has been a large effort to develop and apply computer-aided detection systems for the detection of lung nodules on chest radiographs and chest computed tomography. The essential limitation to computer-aided detection is an inability to learn from new information. To overcome these deficiencies, many groups have turned to deep learning approaches with promising results. In addition to nodule detection, interstitial lung disease recognition, lesion segmentation, diagnosis and patient outcomes have been addressed by deep learning approaches. The purpose of this review article was to cover the current state of the art for deep learning approaches and its limitations, and some of the potential impact on the field of radiology, with specific reference to chest imaging.

Authors

  • Sang Min Lee
    Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
  • Joon Beom Seo
    Department of Radiology, Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul 05505, Korea.
  • Jihye Yun
    Department of Convergence Medicine, Biomedical Engineering Research Center, University of Ulsan College of Medicine, Asan Medical Center, 88 Olympic-Ro 43-Gil Songpa-Gu, Seoul 05505, South Korea.
  • Young-Hoon Cho
    Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center.
  • Jens Vogel-Claussen
    Institute of Diagnostic and Interventional Radiology Hannover Medical School Hannover Germany.
  • Mark L Schiebler
    Department of Radiology, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI.
  • Warren B Gefter
    Department of Radiology, University of Pennsylvania Perelman School of Medicine.
  • Edwin J R van Beek
    Department of Radiology, University of Edinburgh, and Edinburgh Imaging, Queen's Medical Research Institute, Edinburgh, Scotland, UK.
  • Jin Mo Goo
    Department of Radiology, Seoul National College of Medicine, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Korea (H.C., S.H.Y., S.J.P., C.M.P., J.H.L., H. Kim, E.J.H., S.J.Y., J.G.N., C.H.L., J.M.G.); CHESS Center, The First Hospital of Lanzhou University, Lanzhou, China (Q.X., J.L.); Department of Radiology, Seoul National University Bundang Hospital, Gyeonggi-do, Korea (K.H.L.); Department of Internal Medicine, Incheon Medical Center, Incheon, Korea (J.Y.K.); Department of Radiology, Seoul Medical Center, Seoul, Korea (Y.K.L.); Department of Radiology, National Medical Center, Seoul, Korea (H. Ko); Department of Radiology, Myongji Hospital, Gyeonggi-do, Korea (K.H.K.); and Department of Radiology, Chonnam National University Hospital, Gwanju, Korea (Y.H.K.).
  • Kyung Soo Lee
    Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
  • Hiroto Hatabu
    Department of Radiology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.
  • James Gee
    Penn Image Computing and Science Laboratory, Department of Radiology, University of Pennsylvania, Philadelphia, PA.
  • Namkug Kim
    Department of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.