Deep learning for liver tumor diagnosis part II: convolutional neural network interpretation using radiologic imaging features.

Journal: European radiology
PMID:

Abstract

OBJECTIVES: To develop a proof-of-concept "interpretable" deep learning prototype that justifies aspects of its predictions from a pre-trained hepatic lesion classifier.

Authors

  • Clinton J Wang
    CSAIL/EECS, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Charlie A Hamm
    Department of Radiology and Biomedical Imaging, Yale School of Medicine, 333 Cedar Street, New Haven, CT, 06520, USA.
  • Lynn J Savic
    Department of Radiology and Biomedical Imaging, Yale School of Medicine, 333 Cedar Street, New Haven, CT, 06520, USA.
  • Marc Ferrante
    Department of Chronic Diseases and Metabolism (CHROMETA), Translational Research Center for Gastrointestinal Disorders (TARGID), KU Leuven, Herestraat 49, 3000 Leuven, Belgium.
  • Isabel Schobert
    Department of Radiology and Biomedical Imaging, Yale School of Medicine, 333 Cedar Street, New Haven, CT, 06520, USA.
  • Todd Schlachter
    Department of Radiology and Biomedical Imaging, Yale School of Medicine, 333 Cedar Street, New Haven, CT 06520.
  • MingDe Lin
    Philips Research North America, Cambridge, Massachusetts.
  • Jeffrey C Weinreb
    Department of Radiology and Biomedical Imaging, Yale School of Medicine, 333 Cedar Street, New Haven, CT, 06520, USA.
  • James S Duncan
    Biomedical Engineering, Yale University, New Haven, CT 06511, USA.
  • Julius Chapiro
    Department of Radiology and Biomedical Imaging, Yale School of Medicine, 333 Cedar Street, New Haven, CT 06520. Electronic address: julius.chapiro@yale.edu.
  • Brian Letzen
    Department of Radiology and Biomedical Imaging, Yale School of Medicine, 333 Cedar Street, The Anlyan Center, N312A, New Haven, CT 06520.