AIMC Topic: Cholangiocarcinoma

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Activated cancer-associated fibroblasts correlate with poor survival and decreased lymphocyte infiltration in infiltrative type distal cholangiocarcinoma.

Scientific reports
Cancer-associated fibroblasts promote tumor progression through growth facilitation, invasion, and immune evasion. This study investigated the impact of activated cancer-associated fibroblasts (aCAFs) on survival outcomes, immune response, and molecu...

Predicting cisplatin response in cholangiocarcinoma patients using chromosome pattern and related gene expression.

Scientific reports
Cholangiocarcinoma (CCA) is a prevalent bile duct cancer with limited treatment options. Cisplatin-based chemotherapy is a common approach, but response rates vary. Recently, chromosome aberrations have emerged as predictors of chemotherapy response ...

The Application Status of Radiomics-Based Machine Learning in Intrahepatic Cholangiocarcinoma: Systematic Review and Meta-Analysis.

Journal of medical Internet research
BACKGROUND: Over the past few years, radiomics for the detection of intrahepatic cholangiocarcinoma (ICC) has been extensively studied. However, systematic evidence is lacking in the use of radiomics in this domain, which hinders its further developm...

Comparison of MRI and CT based deep learning radiomics analyses and their combination for diagnosing intrahepatic cholangiocarcinoma.

Scientific reports
Intrahepatic cholangiocarcinoma (iCCA) and other subtypes of primary liver cancer (PLC) have overlapping clinical manifestations and radiological characteristics. The objective of this study was to evaluate the efficacy of deep learning (DL) radiomic...

Radiomics and machine learning models for diagnosing microvascular invasion in cholangiocarcinoma: a systematic review and meta-analysis of diagnostic test accuracy studies.

Clinical imaging
PURPOSE: We aimed to systematically assess the value of radiomics/machine learning (ML) models for diagnosing microvascular invasion (MVI) in patients with cholangiocarcinoma (CCA) using various radiologic modalities.

Preoperative blood and CT-image nutritional indicators in short-term outcomes and machine learning survival framework of intrahepatic cholangiocarcinoma.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
BACKGROUND&AIMS: Intrahepatic cholangiocarcinoma (iCCA) is aggressive with limited treatment and poor prognosis. Preoperative nutritional status assessment is crucial for predicting outcomes in patients. This study aimed to compare the predictive cap...

Contrast-enhanced ultrasound-based AI model for multi-classification of focal liver lesions.

Journal of hepatology
BACKGROUND & AIMS: Accurate multi-classification is a prerequisite for appropriate management of focal liver lesions (FLLs). Ultrasound is the most common imaging examination but lacks accuracy. Contrast-enhanced ultrasound (CEUS) offers better perfo...

Machine learning based prediction model for bile leak following hepatectomy for liver cancer.

HPB : the official journal of the International Hepato Pancreato Biliary Association
OBJECTIVE: We sought to develop a machine learning (ML) preoperative model to predict bile leak following hepatectomy for primary and secondary liver cancer.

Textbook outcome in liver surgery for intrahepatic cholangiocarcinoma: defining predictors of an optimal postoperative course using machine learning.

HPB : the official journal of the International Hepato Pancreato Biliary Association
BACKGROUND: We sought to define textbook outcome in liver surgery (TOLS) for intrahepatic cholangiocarcinoma (ICC) by considering the implications of perioperative outcomes on overall survival (OS).

Machine learning-based prognostic prediction and surgical guidance for intrahepatic cholangiocarcinoma.

Bioscience trends
The prognosis following radical surgery for intrahepatic cholangiocarcinoma (ICC) is poor, and optimal follow-up strategies remain unclear, with ongoing debates regarding anatomic resection (AR) versus non-anatomic resection (NAR). This study include...