Artificial intelligence using deep learning to screen for referable and vision-threatening diabetic retinopathy in Africa: a clinical validation study.

Journal: The Lancet. Digital health
Published Date:

Abstract

BACKGROUND: Radical measures are required to identify and reduce blindness due to diabetes to achieve the Sustainable Development Goals by 2030. Therefore, we evaluated the accuracy of an artificial intelligence (AI) model using deep learning in a population-based diabetic retinopathy screening programme in Zambia, a lower-middle-income country.

Authors

  • Valentina Bellemo
    Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
  • Zhan W Lim
    School of Computing, National University of Singapore, Singapore.
  • Gilbert Lim
    School of Computing, National University of Singapore.
  • Quang D Nguyen
    Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
  • Yuchen Xie
    Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
  • Michelle Y T Yip
    Ophthalmology and Visual Science Academic Clinical Program, Duke-NUS Medical School, Singapore.
  • Haslina Hamzah
    Singapore Eye Research Institute, Singapore National Eye Center, Singapore.
  • Jinyi Ho
    Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
  • Xin Q Lee
    Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
  • Wynne Hsu
    School of Computing, National University of Singapore.
  • Mong L Lee
    School of Computing, National University of Singapore, Singapore.
  • Lillian Musonda
    Eye Department, Kitwe Central Eye Hospital, Kitwe, Zambia.
  • Manju Chandran
    Department of Ophthalmology, Frimley Park Hospital NHS Foundation Trust, Camberley, UK.
  • Grace Chipalo-Mutati
    Ophthalmology Department, Lusaka University Teaching Hospital, Lusaka, Zambia.
  • Mulenga Muma
    Ministry of Health, Lusaka, Zambia.
  • Gavin S W Tan
    Singapore Eye Research Institute, Singapore National Eye Centre, Singapore; Ophthalmology and Visual Science Academic Clinical Program, Duke-NUS Medical School, Singapore.
  • Sobha Sivaprasad
    Moorfields Eye Hospital City Road Campus, London, UK.
  • Geeta Menon
    Department of Ophthalmology, Frimley Park Hospital NHS Foundation Trust, Camberley, UK.
  • Tien Y Wong
    Singapore National Eye Center, Duke-NUS Medical School, National University of Singapore, Singapore, Singapore.
  • Daniel S W Ting
    Singapore National Eye Center, Duke-National University of Singapore Medical School, Singapore 168751, Singapore; National Institutes of Health Research Biomedical Research Centre Biomedical Centre, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK. Electronic address: daniel.ting.s.w@singhealth.com.sg.