Atrophy of cerebellar peduncles in essential tremor: a machine learning-based volumetric analysis.

Journal: European radiology
PMID: 31161314

Abstract

BACKGROUND: Subtle cerebellar signs are frequently observed in essential tremor (ET) and may be associated with cerebellar dysfunction. This study aims to evaluate the macrostructural integrity of the superior, middle, and inferior cerebellar peduncles (SCP, MCP, ICP) and cerebellar gray and white matter (GM, WM) volumes in patients with ET, and compare these volumes between patients with and without cerebellar signs (ETc and ETnc).

Authors

  • Shweta Prasad
    Department of Neurology, National Institute of Mental Health and Neurosciences, Bangalore, India; Department of Clinical Neurosciences, National Institute of Mental Health and Neurosciences, Bangalore, India.
  • Umang Pandey
    Symbiosis Center for Medical Image Analysis, Symbiosis International (Deemed) University, Lavale, Mulshi, Pune, Maharashtra, 412115, India.
  • Jitender Saini
    Department of Neuroimaging & Interventional Radiology, National Institute of Mental Health and Neurosciences, Bangalore, India.
  • Madhura Ingalhalikar
    Symbiosis Center of Medical Image Analysis, Symbiosis International (Deemed) University, Pune, India. Electronic address: head@scmia.edu.in.
  • Pramod Kumar Pal
    Department of Neurology, National Institute of Mental Health and Neurosciences, Bangalore, India.

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